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Tigolaner

CAT: 0804-HY-109077-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-109077-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tigolaner (BAY-1272858) acts on γ-aminobutyric acid (GABA) and glutamate-gated chloride channels. Tigolaner has antiparasitic activity[1].
CAS Number
1621436-41-6
Product Name Alternative
BAY-1272858
UNSPSC
12352005
Target
Chloride Channel; GABA Receptor; Parasite
Type
Reference compound
Related Pathways
Anti-infection; Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Infection; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/tigolaner.html
Concentration
10mM
Purity
98.53
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
FC(F)(C(C(C(F)(F)C(F)(F)F)=N1)=C(N2C=C(C(C=C3)=CC(C(NC4(CC4)C#N)=O)=C3Cl)C=N2)N1C)F
Molecular Formula
C21H13ClF8N6O
Molecular Weight
552.81
References & Citations
[1]Mencke N, et al. Plasma pharmacokinetics of tigolaner, emodepside, and praziquantel following topical administration of a combination product (Felpreva®) and of intravenous administration of the individual active ingredients in cats. Curr Res Parasitol Vector Borne Dis. 2023 Jun 22;4:100126.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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