Sphingosine Kinase 2, Long Form, Human

Sphingosine Kinase 2, Long Form, Human

• Background: Rat sphingosine kinase 1 catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (spp)(sphingosine + ATP = sphingosine 1-phosphate + ADP), a lipid mediator with both intra- and extracellular functions. also acts on d-erythro-sphingosine and to a lesser extent sphinganine, but not other lipids, such as d,l-threo-dihydrosphingosine, n,n-dimethylsphingosine, diacylglycerol, ceramide, or phosphatidylinositol. The long form of sphingosine kinase 1, an N-terminal extension, is responsible for FceRI-mediated calcium mobilization and may play a role in other ligand mediated signaling events.
• Synonyms: Sphk2-L, N-terminal-extended Sphingosine Kinase 2
• UniProt: Q9NRA0
• Host: Rabbit
• Isotype: IgG
• Conjugation: Unconjugated
• Type: Blocking Peptide
• Applications: Functional Inhibition
• Field of Research: Lipid Mediators
• Assay Principle: Blocking peptide for use with Human Sphingosine Kinase 2, Long Form antibodies (Cat. No. X1775P , X1880P).
• Stability: See expiration date on vial
• Concentration: See vial for Concentration
• Form: Provided as solution in phosphate buffered saline with 0,08% sodium azide
• Precautions: This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving Humans or animals.
• Storage Conditions: Product should be stored at -20ºC; Aliquot to avoid freeze/thaw cycles