Decorin Antibody

CAT: 0013-GTR18294008-01Size: 20 µgDry Ice: NoHazardous: No

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CAT#:0013-GTR18294008-01Size:20 µg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

Decorin is a small leucine-rich proteoglycan (SLRP) family member that consists of a glycosaminoglycan chain-containing core protein. The core protein contains ten leucine rich repeats that contain sites for glycosylation, flanked by disulfide bond stabilizing loops. Decorin binds to Collagen Type I, II and IV in vivo and promotes the formation of fibers with variations in stability and solubility. The Decorin core protein binds to growth factors, intercellular matrix molecules, such as Fibronectin and Thrombospondin, and to the Decorin endocytosis receptor. Decorin binds to and inhibits TGF may contribute to cartilage destruction that is characteristic of inflammatory joint diseases. For immunostaining, pre-incubation with chondroitinase-SBC or testicular hyaluronidase may be required to expose the epitope.

UniProt

P07585

Reactivity

Human

Immunogen

Recombinant full-length protein was used as the immunogen for the Decorin antibody.

Clonality

Monoclonal

Clone

DCN/6289

Conjugation

Unconjugated

Purification

Protein A/G affinity

Dilution

Flow cytometry: 1-2ug/million cells, Immunofluorescence: 1-2ug/ml, Western blot: 1-2ug/ml, Immunohistochemistry (FFPE) : 1-2ug/ml

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

Optimal dilution of the Decorin antibody should be determined by the researcher.

Tested Applications

FACS, IF, IHC-P, WB

Host or Source

Mouse

Preservative

0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin, 0.05% sodium azide

Isotype

Mouse IgG1, lambda

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