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MSX2 Antibody / Hox-8

CAT: 0800-RQ7311Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ7311Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Homeobox protein MSX-2, also called Homeobox protein Hox-8 (Hox8) is a protein that in humans is encoded by the MSX2 gene. This gene encodes a member of the muscle segment homeobox gene family. The encoded protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Flow cytometry: 1-3ug/million cells, Direct ELISA: 0.1-0.5 µg/mL
UniProt
P35548
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant human protein (amino acids M1-M129) was used as the immunogen for the MSX2 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, FACS, Direct ELISA
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the MSX2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This MSX2 antibody is available for research use only.
Storage Conditions
After reconstitution, the MSX2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the MSX2 antibody should be determined by the researcher.
Image Legend
Flow cytometry testing of human RT4 cells with MSX2 antibody at 1ug/million cells (blocked with goat sera) ; Red=cells alone, Green=isotype control, Blue= MSX2 antibody.

UniProtKB · P35548

Homeobox protein MSX-2

MSX2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P35548
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
MSX2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
D3DQN1, Q53XM4, Q9UD60
Protein keywords

Disease

CraniosynostosisDisease variant

Molecular function

Developmental proteinDNA-bindingRepressor

Domain

Homeobox

Cellular component

Nucleus

Biological process

OsteogenesisTranscriptionTranscription regulation

Technical term

Proteomics identificationReference proteome

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Alternative Products

CatalogName
038645Msx2, CT (Homeobox protein MSX-2, Hox-8, MSX2, HOX8)
MBS6322629-01Msx2, CT (Homeobox protein MSX-2, Hox-8, MSX2, HOX8) (FITC)
MBS6322627-01Msx2, CT (Homeobox protein MSX-2, Hox-8, MSX2, HOX8) (APC)
MBS6322626-01Msx2, CT (Homeobox protein MSX-2, Hox-8, MSX2, HOX8) (AP)
MBS6322628-01Msx2, CT (Homeobox protein MSX-2, Hox-8, MSX2, HOX8) (Biotin)
MBS6322636-01Msx2, CT (Homeobox protein MSX-2, Hox-8, MSX2, HOX8) (PE)
M4692-75Msx2 (Hox8, Homeobox Protein MSX-2, Hox-8)
038645-PEMsx2, CT (Homeobox protein MSX-2, Hox-8, MSX2, HOX8) (PE) discontinued
038645-FITCMsx2, CT (Homeobox protein MSX-2, Hox-8, MSX2, HOX8) (FITC) discontinued
038645-BiotinMsx2, CT (Homeobox protein MSX-2, Hox-8, MSX2, HOX8) (Biotin) discontinued

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