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BRD0539

CAT: 0804-HY-136251-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-136251-01Size:5 mg
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Description
BRD0539 is a Streptococcus pyogenes Cas9 (SpCas9) inhibitor with an IC50 of 22 μM in an in vitro DNA cleavage assay[1].
CAS Number
[1403838-79-8]
UNSPSC
12352005
Target
Bacterial; CRISPR/Cas9
Type
Reference compound
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/brd0539.html
Purity
98.33
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC[C@@H]1NC2=C(C=C(C3=CC=CC=C3F)C=C2)[C@@]4([H])[C@]1([H])CCN4S(=O)(C5=CC=C(C)C=C5)=O
Molecular Formula
C25H25FN2O3S
Molecular Weight
452.54
References & Citations
[1]Basudeb Maji, et al. A High-Throughput Platform to Identify Small-Molecule Inhibitors of CRISPR-Cas9. Cell. 2019 May 2;177 (4) :1067-1079.e19.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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