Recombinant mouse TGF-beta 2/TGFB2 protein (His tag)

Recombinant mouse TGF-beta 2/TGFB2 protein (His tag)

• Background: Transforming growth factor beta 2 (TGF-β2) is a member of TGF-beta superfamily that shares a characteristic cysteine knot structure. Mice with TGF-β2 gene deletion show defects in development of cardiac, lung, craniofacial, limb, spinal column, eye, inner ear and urogenital systems. All TGF-β isoforms signal via the same heteromeric receptor complex, consisting of a ligand binding TGF-β receptor type II (TβR-II), and a TGF-β receptor type I (TβR-I). Signal transduction from the receptor to the nucleus is mediated via SMADs. TGF-β expression is found in cartilage, bone, teeth, muscle, heart, blood vessels, haematopoitic cells, lung, kidney, gut, liver, eye, ear, skin, and the nervous system.
• Abbreviation: TGF-beta 2;TGFB2
• Synonyms: BSC-1 cell growth inhibitor, Cetermin, G-TSF, Glioblastoma-derived T-cell suppressor factor, MGC116892, Polyergin, TGF-beta-2, TGF-beta2, TGFB2, transforming growth factor beta-2
• CAS Number: 9000-83-3
• UniProt: P27090
• Accession Number: P27090
• Host: E. coli
• Origin Species: mouse
• Tag: N-His
• Sequence: Leu 21-Arg 302
• Field of Research: Signal Transduction;Cell biology;Cancer;metabolism;Stem cells
• Purity: > 95% as determined by reducing SDS-PAGE.
• Bioactivity: Not validated for activity
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
• Molecular Weight: 38 kDa
• Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
• Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.