LC3B rabbit pAb

LC3B rabbit pAb

• Description: The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component. [provided by RefSeq, Jul 2008],
• Synonyms: MAP1LC3B; MAP1ALC3; Microtubule-associated proteins 1A/1B light chain 3B; Autophagy-related protein LC3 B; Autophagy-related ubiquitin-like modifier LC3 B; MAP1 light chain 3-like protein 2; MAP1A/MAP1B light chain 3 B; MAP1A/MAP1B LC3 B; Microtubule-associated protein 1 light chain 3 beta
• Gene ID: 81631
• UniProt: Q9GZQ8
• Cellular Locus: Cytoplasmic vesicle, autophagosome membrane ; Lipid-anchor. Endomembrane system ; Lipid-anchor. Mitochondrion membrane ; Lipid-anchor. Cytoplasm, cytoskeleton. Cytoplasmic vesicle. LC3-II binds to the autophagic membranes. LC3-II localizes with the mitochondrial inner membrane during Parkin-mediated mitophagy (PubMed:28017329). Localizes also to discrete punctae along the ciliary axoneme..
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Recombinant Protein of MAP LC3β
• Clonality: Polyclonal
• Validated Applications: WB, IF, IHC
• Stability: 1 year
• Dilution: WB: 1:1000-2000 IHC: 1:200-500 IF 1:200
• Molecular Weight: 14,16kD
• Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.