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RG7713

CAT: 0804-HY-12981-01Size: 10 mM - 1 mLDry Ice: NoHazardous: No
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CAT#:0804-HY-12981-01Size:10 mM - 1 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RG7713 (RO5028442) is a highly potent and selective Brain-Penetrant Vasopressin 1a (V1a) receptor antagonist with Kis of 1 nM (hV1a) and 39 nM (mV1a) .
CAS Number
920022-47-5
Product Name Alternative
RO5028442
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Vasopressin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease; Endocrinology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/RO5028442.html
Purity
99.92
Solubility
DMSO : 20 mg/mL (ultrasonic)
Smiles
O=C(C1=CN(CCN(C)C)C2=C1C=CC(Cl)=C2)N3CCC4(C(C=CC=C5)=C5CO4)CC3
Molecular Formula
C25H28ClN3O2
Molecular Weight
437.96
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Ratni H, et al. Discovery of highly selective brain-penetrant vasopressin 1a antagonists for the potential treatment of autism via a chemogenomic and scaffold hopping approach. J Med Chem. 2015 Mar 12;58 (5) :2275-89.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 1
Isoform
V1a Receptor

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Alternative Products

CatalogName
MBS3845810-01RG7713
A21380-50RG7713 50mg
A21380-25RG7713 25mg
A21380-10RG7713 10mg
A21380-1RG7713 1mg
A21380-100RG7713 100mg
A21380-5RG7713 5mg
S0007-5mgRO 5028442 (RG7713)

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