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ML401

CAT: 0804-HY-116814-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-116814-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ML401, a potent chemical probe, selectively antagonizes EBI2 (also known as GPR183) with an IC50 of 1.03 nM. ML401 displays activity in a chemotaxis assay (IC50=6.24 nM) . ML401 shows good stability and no toxicity[1].
CAS Number
1597489-14-9
Product Name Alternative
(S)-4-Carboxyphenylglycine, (R)-4-Carboxyphenylglycine, (RS)-4-Carboxyphenylglycine
UNSPSC
12352005
Target
EBI2/GPR183
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ml401.html
Purity
99.93
Solubility
DMSO : 10.42 mg/mL (ultrasonic)
Smiles
O=C(/C=C/C1=CC=C(C=C1)Br)N2CCN(CC2)CC3=CC=C(C=C3)Cl
Molecular Formula
C20H20BrClN2O
Molecular Weight
419.74
References & Citations
[1]Ardecky R, et al. Functional Antagonists of EBI-2. Probe Reports from the NIH Molecular Libraries Program [Internet].
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
BA5310-5ML401
A18799-1ML401 1mg
A18799-25ML401 25mg
A18799-500ML401 500mg
A18799-100ML401 100mg
A18799-10ML401 10mg
A18799-5ML401 5mg
A18799-2ML401 2mg
A18799-50ML401 50mg

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