Melperone

Melperone

• CAS Number: 3575-80-2
• UNSPSC Description: Melperone, a butyrophenone, is an antipsychotic agent used for sleep induction which is frequently prescribed in psychiatric setting[1]. Melperone has been used for a variety of indications, including the treatment of schizophrenia, but also for agitation in the elderly[2].
• Target Antigen: Others
• Type: Reference compound
• Related Pathways: Others
• Applications: Neuroscience-Neuromodulation
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/melperone.html
• Purity: 99.24
• Solubility: DMSO : 41.67 mg/mL (ultrasonic)
• Smiles: O=C(C1=CC=C(F)C=C1)CCCN2CCC(C)CC2
• Molecular Weight: 263.35
• References & Citations: [1]Hefner G, et al. Melperone but not bisoprolol or metoprolol is a clinically relevant inhibitor of CYP2D6: evidence from a therapeutic drug monitoring survey. J Neural Transm (Vienna). 2015 Nov;122(11):1609-17.|[2]Bobo WV, et al. Melperone, an aytpical antipsychotic drug with clozapine-like effect on plasma prolactin: contrast with typical neuroleptics. Hum Psychopharmacol. 2009 Jul;24(5):415-22.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: Launched