4-O-Methyl honokiol

4-O-Methyl honokiol

• CAS Number: 68592-15-4
• UNSPSC Description: 4-O-Methyl honokiol is a natural neolignan isolated from Magnolia officinalis, acts as a PPARγ agonist, and inhibtis NF-κB activity, used for cancer and inflammation research.
• Target Antigen: NF-κB; PPAR
• Type: Natural Products
• Related Pathways: Cell Cycle/DNA Damage;Metabolic Enzyme/Protease;NF-κB;Vitamin D Related/Nuclear Receptor
• Applications: COVID-19-anti-virus
• Field of Research: Cancer; Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/4-O-Methyl_honokiol.html
• Purity: 98.18
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: OC1=CC=C(CC=C)C=C1C2=CC(CC=C)=C(OC)C=C2
• Molecular Weight: 280.36
• References & Citations: [1]Lee NJ, et al. 4-O-methylhonokiol, a PPARγ agonist, inhibits prostate tumour growth: p21-mediated suppression of NF-κB activity. Br J Pharmacol. 2013 Mar;168(5):1133-45.|[2]Lee YJ, et al. Inhibitory effect of 4-O-methylhonokiol on lipopolysaccharide-induced neuroinflammation, amyloidogenesis and memory impairment via inhibition of nuclear factor-kappaB in vitro and in vivo models. J Neuroinflammation. 2012 Feb 19;9:35.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported