Mca-Ala-Pro-Lys(Dnp)-OH

• UNSPSC Description:

  Mca-Ala-Pro-Lys(Dnp)-OH, a specific ACE2 quenched fluorogenic substrate, can be used to detect ACE2 activity, such as urinary, heart and lung[1][2].

• Target Antigen:

  Angiotensin-converting Enzyme (ACE)

• Type:

  Dye Reagents

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/mca-ala-pro-lys-dnp-oh.html

• Purity:

  99.80

• Solubility:

  DMSO : 50 mg/mL (ultrasonic)

• Smiles:

  O=C(N1[C@@H](CCC1)C(N[C@H](C(O)=O)CCCCNC2=C([N+]([O-])=O)C=C([N+]([O-])=O)C=C2)=O)[C@H](C)NC(CC(C3=CC=C(OC)C=C3O4)=CC4=O)=O

• Molecular Weight:

  696.66

• References & Citations:

  [1]Liu J, Ji H, et al. Sex differences in renal angiotensin converting enzyme 2 (ACE2) activity are 17β-oestradiol-dependent and sex chromosome-independent. Biol Sex Differ. 2010;1(1):6. Published 2010 Nov 5.|[2]Liang Y, et al. Urinary angiotensin converting enzyme 2 increases in patients with type 2 diabetic mellitus. Kidney Blood Press Res. 2015;40(2):101-110.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

• Clinical Information:

  No Development Reported

• CAS Number:

  305336-82-7