Mca-YVADAP-Lys(Dnp)-OH (TFA)

• UNSPSC Description:

  Mca-YVADAP-Lys(Dnp)-OH TFA is a fluorogenic substrate for caspase-1 and angiotensin-converting enzyme 2 (ACE2)[1].

• Target Antigen:

  Caspase; Cholinesterase (ChE)

• Type:

  Peptides

• Related Pathways:

  Apoptosis;Neuronal Signaling

• Applications:

  Neuroscience-Neurodegeneration

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/mca-yvadap-lys-dnp-oh-tfa.html

• Purity:

  98.85

• Solubility:

  H2O : 22.22 mg/mL (ultrasonic;adjust pH to 9 with 1M NaOH)|H2O : 4.88 mg/mL (ultrasonic;adjust pH to 8 with NaOH)

• Smiles:

  O=C(N[C@H](C(N[C@@H](C(C)C)C(N[C@@H](C)C(N[C@@H](CC(O)=O)C(N[C@@H](C)C(N(CCC1)[C@@H]1C(N[C@H](C(O)=O)CCCCNC(C=CC([N+]([O-])=O)=C2)=C2[N+]([O-])=O)=O)=O)=O)=O)=O)=O)CC(C=C3)=CC=C3O)CC(C(C(O4)=C5)=CC=C5OC)=CC4=O.O=C(O)C(F)(F)F

• Molecular Weight:

  1259.15

• References & Citations:

  [1]Susan Acton, et al. Preparation of amino acid derivatives for modulating angiotensin converting enzyme-2 (ACE-2). US20040082496A1.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)

• Clinical Information:

  No Development Reported