Bis-PEG5-NHS ester

• UNSPSC Description:

  Bis-PEG5-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG5-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• Target Antigen:

  ADC Linker; PROTAC Linkers

• Type:

  ADC Related

• Related Pathways:

  Antibody-drug Conjugate/ADC Related;PROTAC

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/bis-peg5-nhs-ester.html

• Purity:

  99.64

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=C(ON1C(CCC1=O)=O)CCOCCOCCOCCOCCOCCC(ON2C(CCC2=O)=O)=O

• Molecular Weight:

  532.50

• References & Citations:

  [1]Hans-Georg Lerchen, et al. Prodrugs of cytotoxic active agents having enzymatically cleavable groups. WO2018114798A1.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, sealed storage, away from moisture)

• Clinical Information:

  No Development Reported

• CAS Number:

  756526-03-1