Bis-PEG6-NHS ester

• Description:

  Bis-PEG6-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG6-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].

• UNSPSC:

  12352203

• Hazard Statement:

  H315, H319

• Target:

  ADC Linker; PROTAC Linkers

• Type:

  ADC Related

• Related Pathways:

  Antibody-drug Conjugate/ADC Related; PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/bis-peg6-nhs-ester.html

• Purity:

  98.0

• Solubility:

  DMSO : 125 mg/mL (ultrasonic)

• Smiles:

  O=C(ON1C(CCC1=O)=O)CCOCCOCCOCCOCCOCCOCCC(ON2C(CCC2=O)=O)=O

• Molecular Formula:

  C24H36N2O14

• Molecular Weight:

  576.55

• Precautions:

  H315, H319

• References & Citations:

  [1]John L. Magna, et al. Highly potent multimeric e-selectin antagonists. WO2018068010A1.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, sealed storage, away from moisture)

• Scientific Category:

  ADC Related

• Clinical Information:

  No Development Reported

• Isoform:

  Alkyl/ether Linkers; Cleavable Linker; PEG Linkers

• CAS Number:

  [1526718-98-8]