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Recombinant Human CXCL10

CAT: 0014-50193P-50-1Size: 50 µgDry Ice: NoHazardous: No
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CAT#:0014-50193P-50-1Size:50 µg
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Description
Recombinant human CXCL10
CAS Number
9000-83-3
Product Name Alternative
rHuCXCL10, IP-10
UniProt
P02778
Reactivity
Human
Target Antigen
C-X-C motif chemokine 10
Target
CXCL10
Type
Protein
Applications
Migration assay
Concentration
Lot Specific
Dilution
Centrifuge tube prior to resuspending. Recommended at 100ug/ml in sterile distilled water.
Additionnal Information
Endotoxin Level: <0.01 EU per 1ug of protein by LAL method.Migration Assay in cells expressing recombinant CXCR3.
Storage Conditions
12 months from date of receipt, -20°C to -70°C, as supplied. 1 month,- 20°C to -70°C, under sterile conditions after reconstitution. Best if used immediately after reconstitution. Avoid multiple freeze-thaw cycles.
Specificity
CXCL10
Target Background
CXCL10, also known as γ-interferon-inducible protein (IP-10), was originally identified as an IFN-gamma-inducible gene in endothelial cells, fibroblasts, and monocytes. IP-10 signals through the CXCR3 receptor to attract Th1 lymphocytes and monocytes. It also has angiostatic and mitogenic properties on vascular smooth muscle cells. A diverse population of cell types rapidly increases transcription of mRNA encoding IP-10, suggesting that IP-10 might be a key mediator of the IFN-gamma response.

UniProtKB · P02778

C-X-C motif chemokine 10

CXL10_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P02778
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CXCL10
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
Q96QJ5
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Biological process

ChemotaxisInflammatory response

PTM

CitrullinationDisulfide bond

Molecular function

Cytokine

Cellular component

Secreted

Domain

Signal

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