Recombinant Human CXCL10

• Description:

  Recombinant human CXCL10

• Product Name Alternative:

  rHuCXCL10, IP-10

• UniProt:

  P02778

• Reactivity:

  Human

• Target Antigen:

  C-X-C motif chemokine 10

• Target:

  CXCL10

• Type:

  Protein

• Applications:

  Migration assay

• Concentration:

  Lot Specific

• Dilution:

  Centrifuge tube prior to resuspending. Recommended at 100ug/ml in sterile distilled water.

• Additionnal Information:

  Endotoxin Level: <0.01 EU per 1ug of protein by LAL method.Migration Assay in cells expressing recombinant CXCR3.

• Storage Conditions:

  12 months from date of receipt, -20°C to -70°C, as supplied. 1 month,- 20°C to -70°C, under sterile conditions after reconstitution. Best if used immediately after reconstitution. Avoid multiple freeze-thaw cycles.

• Specificity:

  CXCL10

• Target Background:

  CXCL10, also known as γ-interferon-inducible protein (IP-10), was originally identified as an IFN-gamma-inducible gene in endothelial cells, fibroblasts, and monocytes. IP-10 signals through the CXCR3 receptor to attract Th1 lymphocytes and monocytes. It also has angiostatic and mitogenic properties on vascular smooth muscle cells. A diverse population of cell types rapidly increases transcription of mRNA encoding IP-10, suggesting that IP-10 might be a key mediator of the IFN-gamma response.

• CAS Number:

  9000-83-3