L-Glutamic acid-1-13C

L-Glutamic acid-1-13C

• CAS Number: 81201-99-2
• UNSPSC Description: L-Glutamic acid-1-13C is the 13C-labeled L-Glutamic acid. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals.
• Target Antigen: Apoptosis; Endogenous Metabolite; Ferroptosis; iGluR
• Type: Isotope-Labeled Compounds
• Related Pathways: Apoptosis;Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease;Neuronal Signaling
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/l-glutamic-acid-1-13c.html
• Solubility: 10 mM in DMSO
• Smiles: OC(CC[C@H](N)[13C](O)=O)=O
• Molecular Weight: 148.12
• References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Giorguieff MF, et al. Presynaptic effect of L-glutamic acid on the release of dopamine in rat striatal slices. Neurosci Lett. 1977 Oct;6(1):73-7.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported