Products for Research Use Only
RegisterLogin

Setiptiline-d3

CAT: 0804-HY-32329S-01Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-32329S-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Setiptiline-d3 is the deuterium labeled Setiptiline. Setiptiline (Org-8282) is a serotonin receptor antagonist. Setiptiline is a tetracyclic antidepressant (TeCA) which acts as a noradrenergic and specific serotonergic antidepressant (NaSSA) . Setiptiline acts as a norepinephrine reuptake inhibitor, α2-adrenergic receptor antagonist, and serotonin receptor antagonist, likely at the 5-HT2A, 5-HT2C, and/or 5-HT3 subtypes, as well as an H1 receptor inverse agonist/antihistamine[1][2].
CAS Number
1795024-97-3
UNSPSC
12352005
Target
5-HT Receptor; Adrenergic Receptor; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
GPCR/G Protein; Neuronal Signaling; Others
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Solubility
10 mM in DMSO
Smiles
C(N1CC2=C(C=3C(CC=4C2=CC=CC4)=CC=CC3)CC1)([2H])([2H])[2H]
Molecular Formula
C19H16D3N
Molecular Weight
264.38
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Yamada K, Furukawa T. [Behavioral effects of a new antidepressant, setiptiline]. Nihon Yakurigaku Zasshi. 1991 Jan;97 (1) :31-9.|[3]Kamimura M, Aoba A, Yamaguchi N et al. The effect of age on plasma level of setiptiline maleate in depressed patients. Prog Neuropsychopharmacol Biol Psychiatry. 1994 Oct;18 (6) :1015-26.|[4]Kuniyoshi M, Nakamura J, Miura C, Inanaga K. Effectiveness of concomitant setiptiline maleate (Tecipul) on negative symptoms of schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry. 1994 Mar;18 (2) :339-46.|[5]Niho T, Ito C, Shibutani Y, Hashizume H, Yamaguchi K. [Pharmacological properties of MO-8282, a novel antidepressant]. Nihon Yakurigaku Zasshi. 1986 Oct;88 (4) :309-20.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Isoform
5-HT2 Receptor

Related Products

CatalogName
HY-32329-01Setiptiline
HY-32329A-01Setiptiline (maleate)
HY-32329R-01Setiptiline (Standard)
HY-32329AR-01Setiptiline (maleate) (Standard)
HY-15398S3-01Vitamin D3-d3
HY-132348S1Granisetron-d3 (1-methyl-d3)
HY-150954SL-Methionine-d3 (S-methyl-d3) Methyl-d3-sulfonium Chloride
HY-W758392(±) -Ipratropium-d3 Bromide (N-methyl-d3)
HY-B1213AS-01Trimipramine-d3 (N-methyl-d3) (maleate)
HY-104074SPocapavir-d3

Alternative Products

CatalogName
TRC-S280802-10MGSetiptiline-d3
A3815-100Setiptiline
A3816-50Setiptiline maleate
A18090-100Setiptiline 100mg
TRC-D297070-1GDesmethoxy Setiptiline
A18090-50Setiptiline 50mg
A18090-5Setiptiline 5mg

Popular Products