Cefuroxime-d3

• Description :

  Cefuroxime-d3 is deuterium labeled Cefuroxime (sodium) . Cefuroxime sodium is an orally active second-generation cephalosporin antibiotic with increased stability to β-lactamase. Cefuroxime sodium has a broad spectrum activity against Gram-positive and Gram-negative bacteria[1].

• UNSPSC :

  12352005

• Hazard Statement :

  H302-H315-H319-H335

• Target :

  Antibiotic; Bacterial; Isotope-Labeled Compounds

• Type :

  Isotope-Labeled Compounds

• Related Pathways :

  Anti-infection; Others

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Solubility :

  10 mM in DMSO

• Smiles :

  OC(C1=C(COC(N)=O)CS[C@@]([C@@H]2NC(/C(C3=CC=CO3)=N\OC([2H])([2H])[2H])=O)([H])N1C2=O)=O

• Molecular Formula :

  C16H13D3N4O8S

• Molecular Weight :

  427.40

• Precautions :

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

• References & Citations :

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Callaghan, et al. Cefuroxime sodium, a New Cephalosporin Antibiotic: Activity in Vitro. Antimicrob Agents Chemother. 1976 Mar;9 (3) :511-9.|[3]D M Ryan, et al. Cefuroxime sodium, a New Cephalosporin Antibiotic: Activity in Vivo. Antimicrob Agents Chemother. 1976 Mar;9 (3) :520-5.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Isotope-Labeled Compounds

• Clinical Information :

  No Development Reported

• Isoform :

  β-lactam

• CAS Number :

  [1803240-98-3]