Kinase Quenching Buffer Solution
| Catalog number: | _x000D_B2010078 | _x000D_
| Lot number: | _x000D_Batch Dependent | _x000D_
| Expiration date: | _x000D_Batch Dependent | _x000D_
| Volume/Weight | _x000D_1 mL | _x000D_
| pH | _x000D_8 | _x000D_
| Supplied as | _x000D_Ready-to-use solution | _x000D_
| Appearance | _x000D_clear solution | _x000D_
| Applications | _x000D_Stopping kinase reactions | _x000D_
| Shelf-Life | _x000D_1 year from date of manufacture | _x000D_
| Storage: | _x000D_Keep at room temperature | _x000D_
| Keywords: | _x000D_kinase quench buffer, kinase stop buffer, kinase quencher, kinase stopper | _x000D_
| Grade | _x000D_Biotechnology grade. All components are highly pure (minimum 99%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered on a 0.22 um. | _x000D_
| References Related to Kinase Quenching Buffer | _x000D_1: Bhattacharya S, McElhanon KE, Gushchina LV, Weisleder N. Role of_x000D_ phosphatidylinositol-4,5-bisphosphate 3-kinase signaling in vesicular_x000D_ trafficking. Life Sci. 2016 Dec 15;167:39-45.2: Fang C, Xiao Z. Receptor-based 3D-QSAR in Drug Design: Methods and_x000D_ Applications in Kinase Studies. Curr Top Med Chem. 2016;16(13):1463-77.3: Colomer J, Means AR. Physiological roles of the Ca2+/CaM-dependent protein_x000D_ kinase cascade in health and disease. Subcell Biochem. 2007;45:169-214._x000D_ _x000D_ 4: Fabbro D, Cowan-Jacob SW, Möbitz H, Martiny-Baron G. Targeting cancer with_x000D_ small-molecular-weight kinase inhibitors. Methods Mol Biol. 2012;795:1-34._x000D_ _x000D_ 5: Vieth M, Higgs RE, Robertson DH, Shapiro M, Gragg EA, Hemmerle H. Kinomics-_x000D_ structural biology and chemogenomics of kinase inhibitors and targets. Biochim_x000D_ Biophys Acta. 2004 Mar 11;1697(1-2):243-57._x000D_ 6: Qian X, Mitchell J, Wei SJ, Williams J, Petrovich RM, Shears SB. The_x000D_ Ins(1,3,4)P3 5/6-kinase/Ins(3,4,5,6)P4 1-kinase is not a protein kinase. Biochem_x000D_ J. 2005 Jul 15;389(Pt 2):389-95._x000D_ _x000D_ 7: Wang SQ, Goh SS, Chai CLL, Chen A. An efficient synthesis of an exo-enone_x000D_ analogue of LL-Z1640-2 and evaluation of its protein kinase inhibitory_x000D_ activities. Org Biomol Chem. 2016 Jan 14;14(2):639-645._x000D_ 8: Lahiry P, Torkamani A, Schork NJ, Hegele RA. Kinase mutations in human_x000D_ disease: interpreting genotype-phenotype relationships. Nat Rev Genet. 2010_x000D_ Jan;11(1):60-74._x000D_ 9: Graziani A, Ling LE, Endemann G, Carpenter CL, Cantley LC. Purification and_x000D_ characterization of human erythrocyte phosphatidylinositol 4-kinase._x000D_ Phosphatidylinositol 4-kinase and phosphatidylinositol 3-monophosphate 4-kinase_x000D_ are distinct enzymes. Biochem J. 1992 May 15;284 ( Pt 1)(Pt 1):39-45._x000D_ _x000D_ 10: Suga J, Yoshimasa Y, Yamada K, Yamamoto Y, Inoue G, Okamoto M, Hayashi T,_x000D_ Shigemoto M, Kosaki A, Kuzuya H, Nakao K. Differential activation of mitogen-_x000D_ activated protein kinase by insulin and epidermal growth factor in 3T3-L1_x000D_ adipocytes: a possible involvement of PI3-kinase in the activation of the MAP_x000D_ kinase by insulin. Diabetes. 1997 May;46(5):735-41. | _x000D_
| Related Products | _x000D_Biochemical Buffers and Solutions | _x000D_
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