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IRE1/ERN1 Rabbit Polyclonal Antibody

CAT: 0013-GTR17689842Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR17689842Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Anti-IRE1/ERN1 Antibody. Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.
Product Name Alternative
ERN1; hIRE1p; Inositol requiring protein 1; IRE1; Ire1 alpha; IRE1; ERN1; IRE1P; IRE1α
UniProt
O75460
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins.
Immunogen
E. coli-derived human IRE1 recombinant protein (Position: R158-L280) .
Target
Serine/threonine-protein kinase/endoribonuclease IRE1
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Cell Biology, Protein Biochemistry, Signal Transduction
Purification
Immunogen affinity purified.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Dilution
Western blot, 0.1-0.5μg/ml Immunocytochemistry/Immunofluorescence, 2μg/ml Flow Cytometry (Fixed), 1-3μg/1x10^6 cells ELISA, 0.1-0.5μg/ml
Form
Lyophilized
Molecular Weight
170 kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
ELISA, FC, ICC, IF, WB
Host or Source
Rabbit
Preservative
Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Isotype
Rabbit IgG

UniProtKB · O75460

Serine/threonine-protein kinase/endoribonuclease IRE1

ERN1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O75460
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ERN1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
A1L457, A8K8N8, A8MXS7, Q59EE2
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

ADP-ribosylationDisulfide bondGlycoproteinPhosphoprotein

Coding sequence diversity

Alternative splicing

Biological process

ApoptosisTranscriptionTranscription regulationUnfolded protein response

Ligand

ATP-bindingMagnesiumMetal-bindingNucleotide-binding

Cellular component

Endoplasmic reticulumMembrane

Molecular function

HydrolaseKinaseMultifunctional enzymeSerine/threonine-protein kinaseTransferase

Domain

SignalTransmembraneTransmembrane helix

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