Human BPHL Protein

• Description:

  Human BPHL Protein_x000D_ Catalog number: B2011646_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 100 µg_x000D_ Molecular Weight or Concentration: 0.5 mg/mL_x000D_ Supplied as: Solution_x000D_ Applications: molecular tool for various biochemical applications_x000D_ Storage: -20 °C_x000D_ Keywords: VACVASE, Valacyclovir hydrolase protein, BPH-RP protein, MCNAA protein_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Marsillach J, Suzuki SM, Richter RJ, McDonald MG, Rademacher PM, MacCoss MJ, Hsieh EJ, Rettie AE, Furlong CE. Human valacyclovir hydrolase/biphenyl hydrolase-like protein is a highly efficient homocysteine thiolactonase PLoS One. 2014 Oct 15;9(10):e110054._x000D_ 2: Kim I, Chu XY, Kim S, Provoda CJ, Lee KD, Amidon GL. Identification of a human valacyclovirase: biphenyl hydrolase-like protein as valacyclovir hydrolase J Biol Chem. 2003 Jul 11;278(28):25348-56._x000D_ 3: Puente XS, Pendás AM, López-otín C. Structural characterization and chromosomal localization of the gene encoding human biphenyl hydrolase-related protein (BPHL) Genomics. 1998 Aug 1;51(3):459-62._x000D_ 4: Kim I, Crippen GM, Amidon GL. Structure and specificity of a human valacyclovir activating enzyme: a homology model of BPHL Mol Pharm. 2004 Nov-Dec;1(6):434-46._x000D_ 5: Shenoy VM, Thompson BR, Shi J, Zhu HJ, Smith DE, Amidon GL. Chemoproteomic Identification of Serine Hydrolase RBBP9 as a Valacyclovir-Activating Enzyme Mol Pharm. 2020 May 4;17(5):1706-1714._x000D_ 6: Tao W, Zhao D, Sun M, Li M, Zhang X, He Z, Sun Y, Sun J. Enzymatic activation of double-targeted 5'-O-L-valyl-decitabine prodrug by biphenyl hydrolase-like protein and its molecular design basis Drug Deliv Transl Res. 2017 Apr;7(2):304-311._x000D_ 7: Chu C, Liu BZ, Zhong L, Wu XJ, Zhu D, Wu Y. [Identification of interaction between BPHL and PML-C] Chu C, Liu BZ, Zhong L, Wu XJ, Zhu D, Wu Y._x000D_ 8: Kim I, Song X, Vig BS, Mittal S, Shin HC, Lorenzi PJ, Amidon GL. A novel nucleoside prodrug-activating enzyme: substrate specificity of biphenyl hydrolase-like protein Mol Pharm. 2004 Mar-Apr;1(2):117-27._x000D_ 9: Hu Y, Epling D, Shi J, Song F, Tsume Y, Zhu HJ, Amidon GL, Smith DE. Effect of biphenyl hydrolase-like (BPHL) gene disruption on the intestinal stability, permeability and absorption of valacyclovir in wildtype and Bphl knockout mice Biochem Pharmacol. 2018 Oct;156:147-156._x000D_ 10: Melk A, Mansfield ES, Hsieh SC, Hernandez-Boussard T, Grimm P, Rayner DC, Halloran PF, Sarwal MM. Transcriptional analysis of the molecular basis of human kidney aging using cDNA microarray profiling Kidney Int. 2005 Dec;68(6):2667-79. _x000D_ _x000D_ Products Related to Human BPHL Protein can be found at Proteins

• Short Description:

  Catalog Number: B2011646 (100 µg)

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height:

  0.5

• Height :

  0.5