TIM-098a

CAT: 0804-HY-162388Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-162388Size:1 Each
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Description
TIM-098a is a selective AAK1 inhibitor with an IC50 of 0.24 µM. TIM-098a has no inhibitory activity against CaMKK isoforms. TIM-098a inhibits AAK1-regulated endocytosis by suppressing AAK1 kinase activity[1].
UNSPSC
12352005
Target
AAK1
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/tim-098a.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=CC2=CC(O)=CC3=C12)N4C3=NC5=CC(N)=CC=C54
Molecular Formula
C18H11N3O2
Molecular Weight
301.30
References & Citations
[1]Akari Yoshida, et al. Development of a novel AAK1 inhibitor via Kinobeads-based screening. Sci Rep. 2024 Mar 20;14 (1) :6723.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MUC5AC

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