TIM-098a

• UNSPSC Description:

  TIM-098a is a selective AAK1 inhibitor with an IC50 of 0.24 µM. TIM-098a has no inhibitory activity against CaMKK isoforms. TIM-098a inhibits AAK1-regulated endocytosis by suppressing AAK1 kinase activity[1].

• Target Antigen:

  AAK1

• Type:

  Reference compound

• Related Pathways:

  Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/tim-098a.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=CC=CC2=CC(O)=CC3=C12)N4C3=NC5=CC(N)=CC=C54

• Molecular Weight:

  301.30

• References & Citations:

  [1]Akari Yoshida, et al. Development of a novel AAK1 inhibitor via Kinobeads-based screening. Sci Rep. 2024 Mar 20;14(1):6723.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported