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DV-B-120

CAT: 0804-HY-162485-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-162485-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DV-B-120 is a competitive inhibitor for dengue virus (DENV) with IC50s of 5.35, 7.39, 10.49 and 8.58 μM, for DENV-1, DENV-2, DENV-3 and DENV-4, respectively, by inhibiting NS2B-NS3 protease. DV-B-120 exhibits antiviral activity through inhibition of DENV replication[1].
UNSPSC
12352005
Target
Dengue Virus; Virus Protease
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/dv-b-120.html
Purity
98.49
Solubility
DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=S(C1=CC=C(C)C=C1)(/N=C2C=C(NS(=O)(C3=CC=CC=C3)=O)C(C4=C/2C=CC=C4)=O)=O
Molecular Formula
C23H18N2O5S2
Molecular Weight
466.53
References & Citations
[1]Huang Y-J, et al., Exploring the therapeutic potential of DV-B-120 as an inhibitor of dengue virus infection. J Virol. 2024 Apr 16;98 (4) :e0125823.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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