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Harpagide (Standard)

CAT: 0804-HY-N0397RSize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-N0397RSize:1 Each
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Description
Harpagide (Standard) is the analytical standard of Harpagide. This product is intended for research and analytical applications. Harpagide is a class of iridoid glycoside isolated from Scrophularia ningpoensis and has antiparasitic activity, which exhibits good in vitro trypanocidal activities against African trypanosomes (T.b. rhodesiense) with an IC50 of 21 μg/mL. Harpagide exerts significant antileishmanial activity against L. donovani with an IC50 value of 2.0 μg/mL. Harpagide also possess significant anti-inflammatory activities[1][2].
CAS Number
6926-08-5
UNSPSC
12352005
Target
Parasite; Reference Standards
Type
Reference Standards
Related Pathways
Anti-infection; Others
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/harpagide-standard.html
Smiles
O[C@H]1[C@H](O)[C@@H](O)[C@]([H])(O[C@@H]2OC=C[C@]3(O)[C@@]2([H])[C@](O)(C)C[C@H]3O)O[C@@H]1CO
Molecular Formula
C15H24O10
Molecular Weight
364.35
References & Citations
[1]Tasdemir D, et al. Evaluation of antiprotozoal and antimycobacterial activities of the resin glycosides and the other metabolites of Scrophularia cryptophila. Phytomedicine. 2008 Mar;15 (3) :209-15.|[2]Zhang L, et al. Effects of β-glucosidase hydrolyzed products of harpagide and harpagoside on cyclooxygenase-2 (COX-2) in vitro. Bioorg Med Chem. 2011 Aug 15;19 (16) :4882-6.|[3] Háznagy-Radnai E, et al. Cytotoxic activities of Stachys species. Fitoterapia. 2008 Dec;79 (7-8) :595-7.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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