Products for Research Use Only
RegisterLogin

Harpagide

CAT: 0804-HY-N0397-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-N0397-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Harpagide is a class of iridoid glycoside isolated from Scrophularia ningpoensis and has antiparasitic activity, which exhibits good in vitro trypanocidal activities against African trypanosomes (T.b. rhodesiense) with an IC50 of 21 μg/mL. Harpagide exerts significant antileishmanial activity against L. donovani with an IC50 value of 2.0 μg/mL. Harpagide also possess significant anti-inflammatory activities[1][2].
CAS Number
6926-08-5
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Parasite
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/harpagide.html
Purity
99.97
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O[C@H]1[C@H](O)[C@@H](O)[C@]([H])(O[C@@H]2OC=C[C@]3(O)[C@@]2([H])[C@](O)(C)C[C@H]3O)O[C@@H]1CO
Molecular Formula
C15H24O10
Molecular Weight
364.35
Precautions
H302, H315, H319, H335
References & Citations
[1]Tasdemir D, et al. Evaluation of antiprotozoal and antimycobacterial activities of the resin glycosides and the other metabolites of Scrophularia cryptophila. Phytomedicine. 2008 Mar;15 (3) :209-15.|[2]Zhang L, et al. Effects of β-glucosidase hydrolyzed products of harpagide and harpagoside on cyclooxygenase-2 (COX-2) in vitro. Bioorg Med Chem. 2011 Aug 15;19 (16) :4882-6.|[3] Háznagy-Radnai E, et al. Cytotoxic activities of Stachys species. Fitoterapia. 2008 Dec;79 (7-8) :595-7.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Leishmania; Trypanosoma

Related Products

CatalogName
HY-N0396-01Harpagoside
HY-N0396RHarpagoside (Standard)

Alternative Products

CatalogName
MBS3840544-01Harpagide
371528Harpagide discontinued
TRC-H105270-10MGHarpagide (90%)
A14703-50Harpagide 50mg
A14703-25Harpagide 25mg
A14703-10Harpagide 10mg
A14703-5Harpagide 5mg

Popular Products