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Eif4b Rabbit pAb

CAT: 0855-ES20867-02Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0855-ES20867-02Size:100 µL
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Background
CRequired for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F., similarity:Contains 1 RRM (RNA recognition motif) domain., subunit:Self-associates and interacts with EIF3 p170 subunit.
Description
CRequired for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F. similarity: Contains 1 RRM (RNA recognition motif) domain. subunit: Self-associates and interacts with EIF3 p170 subunit.
Product Name Alternative
Eukaryotic translation initiation factor 4B (eIF-4B)
UniProt
P23588
Swiss Prot
P23588
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human Eif4b AA range: 209-259
Target
EIF4B
Clonality
Polyclonal
Source
Rabbit
Applications
IHC; WB
Concentration
1 mg/ml
Dilution
IHC-p1:50-200 , WB 1:1000-2000
Buffer
-20°C/1 year
Molecular Weight
69kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
69kD
Fragment
IgG
Subcellular Location
Cytosol, polysome, eukaryotic translation initiation factor 4F complex, dendrite, neuronal cell body
Other Product Names
Eukaryotic translation initiation factor 4B (eIF-4B)
Gene ID (Human)
1975

UniProtKB · P23588

Eukaryotic translation initiation factor 4B

IF4B_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P23588
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
EIF4B
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
eIF-4B
EC number
—
Processing
—
Secondary accessions
B4DS13, Q4G0E3, Q53HQ2, Q6GPH5, Q6IB46, Q8WYK5
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondPhosphoproteinUbl conjugation

Coding sequence diversity

Alternative splicing

Molecular function

Initiation factorRNA-binding

Biological process

Protein biosynthesis

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