EIF2Bγ rabbit pAb

• Background:

  The protein encoded by this gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]

• Description:

  The protein encoded by this gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009],

• UniProt:

  Q9NR50

• Swiss Prot:

  Q9NR50

• Reactivity:

  Human; Mouse

• Immunogen:

  Synthesized peptide derived from eIF2Bγ . at AA range: 240-320

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB; ELISA

• Concentration:

  1 mg/ml

• Dilution:

  Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.

• Molecular Weight:

  50kD

• Storage Conditions:

  -20°C/1 year

• Observed Molecular Weight:

  50kD

• Fragment:

  IgG

• Subcellular Location:

  Cytoplasm, cytosol, eukaryotic translation initiation factor 2B complex

• Other Product Names:

  EIF2B3; Translation initiation factor eIF-2B subunit gamma; eIF-2B GDP-GTP exchange factor subunit gamma

• Gene ID (Human):

  8891