Canrenone-d6

CAT: 0804-HY-B1438SSize: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-B1438SSize:1 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Canrenone-d6 is the deuterium labeled Canrenone. Canrenone (Aldadiene) is an aldosterone antagonist extensively used as a diuretic agent.
Product Name Alternative
Aldadiene-d6; SC9376-d6
UNSPSC
12352005
Hazard Statement
H351, H411
Target
Endogenous Metabolite; Isotope-Labeled Compounds; Mineralocorticoid Receptor
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease; Others; Vitamin D Related/Nuclear Receptor
Field of Research
Cardiovascular Disease
Purity
98.78
Solubility
10 mM in DMSO
Smiles
C[C@@]12[C@@]3(OC(C([2H])([2H])C3)=O)CC[C@@]1([H])[C@@]4([H])[C@]([C@@]5(C(C=C4[2H])=C([2H])C(C([2H])([2H])C5)=O)C)([H])CC2
Molecular Formula
C22H22D6O3
Molecular Weight
346.49
Precautions
H351, H411
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Erbler HC, et al. On the mechanism of the inhibitory action of the spirolactone SC 9376 (aldadiene) on the production of corticosteroids in rat adrenals in vitro. Naunyn Schmiedebergs Arch Pharmacol. 1973;277 (2) :139-49.|[3]Caligiuri A, et al. Antifibrogenic effects of canrenone, an antialdosteronic drug, on human hepatic stellate cells. Gastroenterology. 2003 Feb;124 (2) :504-20.|[4]Erbler HC, et al. Effect of spironolactone and its main metabolite canrenone on the renin-angiotensin-aldosterone-system during long-term treatment in rats. Acta Endocrinol (Copenh) . 1979 Jan;90 (1) :147-56.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

Related Products

CatalogName
HY-B1438-01Canrenone
HY-B1438S1-01Canrenone-d4
HY-B1438R-01Canrenone (Standard)
HY-B1438S2-01Canrenone-d7
HY-110225-01Levetiracetam-d6 (ring-d6)
HY-13331S1Clascoterone-d6
HY-90001SRitonavir-d6
HY-B0674S1Ebastine-d6
HY-B1776S-01Spermidine-d6
HY-156248SSpironolactone-d6

Alternative Products

CatalogName
MF-0101625-01Canrenone-d6
TRC-C175612-10MGCanrenone-d6 (Major)
540056Canrenone
TRC-C175615-500MGDelta9-Canrenone
MF-0101626-01Canrenone-d4
A17574-25Canrenone 25mg
A17574-100Canrenone 100mg
sc-504606Δ9-Canrenone

Popular Products