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Trimethadione (Standard)

CAT: 0804-HY-A0092R-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-A0092R-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Trimethadione (Standard) is the analytical standard of Trimethadione. This product is intended for research and analytical applications. Trimethadione (3,5,5, -Trimethyloxazolidine-2,4-dione) is an oxazolidinedione anticonvulsant agent widely used against absences seizures. Trimethadione also is a T-type calcium channel blocker which has antihyperalgesic effects[1][2].
CAS Number
127-48-0
Product Name Alternative
3,5,5, -Trimethyloxazolidine-2,4-dione (Standard)
UNSPSC
12352005
Target
Calcium Channel; Reference Standards
Type
Reference Standards
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling; Others
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/trimethadione-standard.html
Smiles
O=C(N1C)OC(C)(C)C1=O
Molecular Formula
C6H9NO3
Molecular Weight
143.14
References & Citations
[1]Pastore V, et, al. Synthesis and anticonvulsant activity of bioisosteres of trimethadione, N-derivative-1,2,3-oxathiazolidine-4-one-2,2-dioxides from α-hydroxyamides. Bioorg Med Chem. 2013 Feb 15;21 (4) :841-6.|[2]Barton ME, et, al. The antihyperalgesic effects of the T-type calcium channel blockers ethosuximide, trimethadione, and mibefradil. Eur J Pharmacol. 2005 Oct 3;521 (1-3) :79-85.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

Chemical Information

Trimethadione

Trimethadione can cause developmental toxicity according to state or federal government labeling requirements.

CAS Number127-48-0
PubChem CID5576
IUPAC Name3,5,5-trimethyl-1,3-oxazolidine-2,4-dione
Molecular FormulaC6H9NO3
Molecular Weight143.14
XLogP0.3
Topological Polar Surface Area46.6
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count3
Rotatable Bond Count0
Heavy Atom Count10
Formal Charge0
Complexity197
SMILES
CC1(C(=O)N(C(=O)O1)C)C
InChI
InChI=1S/C6H9NO3/c1-6(2)4(8)7(3)5(9)10-6/h1-3H3
InChIKey
IRYJRGCIQBGHIV-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Trimethadione
CAS: 127-48-0
CID: 5576
Formula: C6H9NO3
MW: 143.14
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight143.14
XLogP30.3
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count3
Rotatable Bond Count0
Exact Mass143.058243149
Monoisotopic Mass143.058243149
Topological Polar Surface Area46.6 Ų
Heavy Atom Count10
Formal Charge0
Complexity197
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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T0283-01Trimethadione
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A17688-200Trimethadione 200mg
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