Products for Research Use Only
RegisterLogin

Trimethadione

CAT: 0804-HY-A0092-01Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-A0092-01Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Trimethadione (3,5,5, -Trimethyloxazolidine-2,4-dione) is an oxazolidinedione anticonvulsant agent widely used against absences seizures. Trimethadione also is a T-type calcium channel blocker which has antihyperalgesic effects[1][2].
CAS Number
127-48-0
Product Name Alternative
3,5,5, -Trimethyloxazolidine-2,4-dione
UNSPSC
12352005
Hazard Statement
H312, H332, H360
Target
Calcium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Trimethadione.html
Concentration
10mM
Purity
99.59
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(N1C)OC(C)(C)C1=O
Molecular Formula
C6H9NO3
Molecular Weight
143.14
Precautions
H312, H332, H360
References & Citations
[1]Pastore V, et, al. Synthesis and anticonvulsant activity of bioisosteres of trimethadione, N-derivative-1,2,3-oxathiazolidine-4-one-2,2-dioxides from α-hydroxyamides. Bioorg Med Chem. 2013 Feb 15;21 (4) :841-6.|[2]Barton ME, et, al. The antihyperalgesic effects of the T-type calcium channel blockers ethosuximide, trimethadione, and mibefradil. Eur J Pharmacol. 2005 Oct 3;521 (1-3) :79-85.|[3]Shen H, et al., Prophylactic and therapeutic functions of T-type calcium blockers against noise-induced hearing loss. Hear Res. 2007 Apr;226 (1-2) :52-60.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
T-type calcium channel

Alternative Products

CatalogName
318950Trimethadione
A17688-200Trimethadione 200mg
A17688-100Trimethadione 100mg
A17688-50Trimethadione 50mg

Popular Products