CID 5951923

• Description:

  CID 5951923 is a potent inhibitor of Krüppel-like factor 5 (KLF5), with an IC50 of 603 nM. CID 5951923 can inhibit proliferation of cancer cells in vitro[1].

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  KLF

• Type:

  Reference compound

• Related Pathways:

  MAPK/ERK Pathway

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/cid-5951923.html

• Purity:

  98.87

• Solubility:

  DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles:

  O=C(OCC(N(C)C(CC1)CS1(=O)=O)=O)/C=C/C2=CC=CC([N+]([O-])=O)=C2

• Molecular Formula:

  C16H18N2O7S

• Molecular Weight:

  382.39

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Bialkowska AB, et, al. Identification of small-molecule inhibitors of the colorectal cancer oncogene Krüppel-like factor 5 expression by ultrahigh-throughput screening. Mol Cancer Ther. 2011 Nov; 10 (11) : 2043-51.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [749872-43-3]