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CID 2011756

CAT: 0804-HY-13454-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-13454-01Size:5 mg
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Description
CID 2011756 is an ATP competitive PKD inhibitor, with an IC50 of 3.2 μM for PKD1 in cell free assay, and also shows cellular pan-PKD inhibitory activity against PKD2 and PKD3 (IC50, 0.6 and 0.7 μM, respectively) . CID 2011756 also has antitumor activity.
CAS Number
638156-11-3
UNSPSC
12352005
Hazard Statement
H302, H319
Target
PKD
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/CID-2011756.html
Concentration
10mM
Purity
96.98
Solubility
DMSO : 20 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=C(C2=CC=CC(Cl)=C2)O1)NC3=CC=C(CN4CCOCC4)C=C3
Molecular Formula
C22H21ClN2O3
Molecular Weight
396.87
Precautions
H302, H319
References & Citations
[1]Sharlow ER, et al. Discovery of diverse small molecule chemotypes with cell-based PKD1 inhibitory activity. PLoS One. 2011;6 (10) :e25134.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PKD1; PKD2; PKD3

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