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Kv11.3 rabbit pAb

CAT: 0855-ES20682-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES20682-01Size:50 µL
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Background
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. There are at least two alternatively spliced transcript variants derived from this gene and encoding distinct isoforms. [provided by RefSeq, Jul 2008]
Description
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. There are at least two alternatively spliced transcript variants derived from this gene and encoding distinct isoforms. [provided by RefSeq, Jul 2008],
UniProt
Q9NS40
Swiss Prot
Q9NS40
Reactivity
Human; Rat; Mouse
Immunogen
Synthetic Peptide of Kv11.3. AA range 1130-1180
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF
Concentration
1 mg/ml
Dilution
WB 1:1000-2000, IHC 1:100-200
Molecular Weight
83135kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
83135kD
Fragment
IgG
Subcellular Location
Membrane; Multi-pass membrane protein.
Other Product Names
Potassium voltage-gated channel subfamily H member 7 (Ether-a-go-go-related gene potassium channel 3; ERG-3; Eag-related protein 3; Ether-a-go-go-related protein 3; hERG-3; Voltage-gated potassium channel subunit Kv11.3)
Gene ID (Human)
90134

UniProtKB · Q9NS40

Voltage-gated inwardly rectifying potassium channel KCNH7

KCNH7_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9NS40
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
KCNH7
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q53QU4, Q53TB7, Q53TP9, Q8IV15
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneMembrane

Domain

Coiled coilTransmembraneTransmembrane helix

PTM

GlycoproteinPhosphoprotein

Molecular function

Ion channelPotassium channelVoltage-gated channel

Biological process

Ion transportPotassium transportTransport

Ligand

Potassium