ESAT6 Epitope

• UNSPSC Description:

  ESAT6 Epitope is a known CD4+ T cell epitope in early secretory antigen target gene 6 (ESAT6) that binds to major histocompatibility complex MHC class I with nanometer affinity (IC50=180 nM). ESAT6 Epitope can be used to enhance BCG-induced anti-Mycobacterium tuberculosis cellular immunity[1].

• Target Antigen:

  Bacterial

• Type:

  Peptides

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/esat6-epitope.html

• Purity:

  96.86

• Smiles:

  OC(CNC([C@H](CCC(N)=O)NC([C@H]([C@@H](C)CC)NC([C@H](C)NC([C@H](CO)NC([C@H](C)NC([C@H](C)NC([C@H](C)NC([C@H](CCC(O)=O)NC([C@H]([C@@H](C)CC)NC(CNC([C@H](C)NC([C@H](CC1=CC=CC=C1)NC([C@H](CC(N)=O)NC([C@@H](NC([C@H](CCC(N)=O)NC([C@H](CCC(N)=O)NC([C@H](CCC(O)=O)NC([C@H]([C@H](O)C)NC([C@@H](N)CCSC)=O)=O)=O)=O)=O)CC2=CNC3=CC=CC=C23)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

• Molecular Weight:

  2123.30

• References & Citations:

  [1]Chesson, et al. "Nanoscale peptide self-assemblies boost BCG-primed cellular immunity against Mycobacterium tuberculosis." Scientific reports 8.1 (2018): 12519.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

• Clinical Information:

  No Development Reported

• CAS Number:

  183273-40-7