ESAT6 Epitope

ESAT6 Epitope

• CAS Number: 183273-40-7
• UNSPSC Description: ESAT6 Epitope is a known CD4+ T cell epitope in early secretory antigen target gene 6 (ESAT6) that binds to major histocompatibility complex MHC class I with nanometer affinity (IC50=180 nM). ESAT6 Epitope can be used to enhance BCG-induced anti-Mycobacterium tuberculosis cellular immunity[1].
• Target Antigen: Bacterial
• Type: Peptides
• Related Pathways: Anti-infection
• Applications: COVID-19-immunoregulation
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/esat6-epitope.html
• Purity: 96.86
• Smiles: OC(CNC([C@H](CCC(N)=O)NC([C@H]([C@@H](C)CC)NC([C@H](C)NC([C@H](CO)NC([C@H](C)NC([C@H](C)NC([C@H](C)NC([C@H](CCC(O)=O)NC([C@H]([C@@H](C)CC)NC(CNC([C@H](C)NC([C@H](CC1=CC=CC=C1)NC([C@H](CC(N)=O)NC([C@@H](NC([C@H](CCC(N)=O)NC([C@H](CCC(N)=O)NC([C@H](CCC(O)=O)NC([C@H]([C@H](O)C)NC([C@@H](N)CCSC)=O)=O)=O)=O)=O)CC2=CNC3=CC=CC=C23)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
• Molecular Weight: 2123.30
• References & Citations: [1]Chesson, et al. "Nanoscale peptide self-assemblies boost BCG-primed cellular immunity against Mycobacterium tuberculosis." Scientific reports 8.1 (2018): 12519.
• Shipping Conditions: Blue Ice
• Storage Conditions: -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
• Clinical Information: No Development Reported