2F5 epitope

• Description:

  2F5 epitope, a peptide gp41 (659-671), comprises the entire epitope for one of the three known antibodies capable of neutralizing a broad spectrum of primary HIV-1 isolates and is the only such epitope that is sequential. 2F5 epitope is recognized by broadly neutralizing antibodies 2F5[1][2].

• UNSPSC:

  12352209

• Target:

  HIV

• Type:

  Peptides

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/2f5-epitope.html

• Solubility:

  10 mM in DMSO

• Smiles:

  OC (CC[C@H] (N) C (N[C@@H] (CC (C) C) C (N[C@@H] (CC (C) C) C (N[C@@H] (CCC (O) =O) C (N[C@@H] (CC (C) C) C (N[C@@H] (CC (O) =O) C (N[C@@H] (CCCCN) C (N[C@@H] (CC1=CNC2=CC=CC=C12) C (N[C@@H] (C) C (N[C@@H] (CO) C (N[C@@H] (CC (C) C) C (N[C@H] (C (N[C@H] (C (O) =O) CC (N) =O) =O) CC3=CNC4=CC=CC=C34) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O

• Molecular Formula:

  C76H113N17O22

• Molecular Weight:

  1616.81

• References & Citations:

  [1]Zohar Biron, et al. A monomeric 3 (10) -helix is formed in water by a 13-residue peptide representing the neutralizing determinant of HIV-1 on gp41. Biochemistry. 2002 Oct 22;41 (42) :12687-96.|[2]Yougang Zhai, et al. Bovine papillomavirus-like particles presenting conserved epitopes from membrane-proximal external region of HIV-1 gp41 induced mucosal and systemic antibodies. Vaccine. 2013 Nov 4;31 (46) :5422-9.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Peptides

• Clinical Information:

  No Development Reported

• CAS Number:

  470704-11-1