2F5 epitope

2F5 epitope

• CAS Number: 470704-11-1
• UNSPSC Description: 2F5 epitope, a peptide gp41 (659-671), comprises the entire epitope for one of the three known antibodies capable of neutralizing a broad spectrum of primary HIV-1 isolates and is the only such epitope that is sequential. 2F5 epitope is recognized by broadly neutralizing antibodies 2F5[1][2].
• Target Antigen: HIV
• Type: Peptides
• Related Pathways: Anti-infection
• Applications: COVID-19-anti-virus
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/2f5-epitope.html
• Solubility: 10 mM in DMSO
• Smiles: OC(CC[C@H](N)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CC(O)=O)C(N[C@@H](CCCCN)C(N[C@@H](CC1=CNC2=CC=CC=C12)C(N[C@@H](C)C(N[C@@H](CO)C(N[C@@H](CC(C)C)C(N[C@H](C(N[C@H](C(O)=O)CC(N)=O)=O)CC3=CNC4=CC=CC=C34)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
• Molecular Weight: 1616.81
• References & Citations: [1]Zohar Biron, et al. A monomeric 3(10)-helix is formed in water by a 13-residue peptide representing the neutralizing determinant of HIV-1 on gp41. Biochemistry. 2002 Oct 22;41(42):12687-96.|[2]Yougang Zhai, et al. Bovine papillomavirus-like particles presenting conserved epitopes from membrane-proximal external region of HIV-1 gp41 induced mucosal and systemic antibodies. Vaccine. 2013 Nov 4;31(46):5422-9.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported