BX517
CAT:
804-HY-13842-02
Size:
5 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
BX517
- CAS Number: 850717-64-5
- UNSPSC Description: BX517 is a potent and selective inhibitor of PDK1 with IC50 of 6 nM.
- Target Antigen: PDK-1
- Type: Reference compound
- Related Pathways: PI3K/Akt/mTOR
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/BX517.html
- Smiles: NC(NC1=CC=C(NC(/C2=C(C)\C3=CC=CN3)=O)C2=C1)=O
- Molecular Weight: 282.30
- References & Citations: [1]Islam I, et al. Indolinone based phosphoinositide-dependent kinase-1 (PDK1) inhibitors. Part 2: optimization of BX-517. Bioorg Med Chem Lett. 2007 Jul 15;17(14):3819-25.|[2]Islam I, et al. Indolinone based phosphoinositide-dependent kinase-1 (PDK1) inhibitors. Part 1: design, synthesis and biological activity. Bioorg Med Chem Lett. 2007 Jul 15;17(14):3814-8.
- Shipping Conditions: Room Temperature