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5,6,7-Trimethoxyflavone

CAT: 0804-HY-110398-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-110398-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
5,6,7-Trimethoxyflavone is a flavonoid compound that can be isolated from plants Callicarpa japonica. 5,6,7-Trimethoxyflavone exhibits antiviral and anti-inflammatory activities through inhibition of NF-κB/AP-1/STAT signaling pathway[1][2].
CAS Number
973-67-1
Product Name Alternative
Baicalein trimethyl ether
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
AP-1; CMV; Enterovirus; HSV; NF-κB; STAT
Type
Natural Products
Related Pathways
Anti-infection; Immunology/Inflammation; JAK/STAT Signaling; NF-κB; Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/5-6-7-trimethoxyflavone.html
Purity
98.76
Solubility
DMSO : 33.33 mg/mL (ultrasonic)
Smiles
O=C1C=C(C2=CC=CC=C2)OC3=CC(OC)=C(OC)C(OC)=C13
Molecular Formula
C18H16O5
Molecular Weight
312.32
Precautions
H302, H315, H319, H335
References & Citations
[1]Hayashi K, et al., Antiviral activity of 5,6,7-trimethoxyflavone and its potentiation of the antiherpes activity of acyclovir. J Antimicrob Chemother. 1997 Jun;39 (6) :821-4.|[2]Rim HK, et al., 5,6,7-trimethoxyflavone suppresses pro-inflammatory mediators in lipopolysaccharide-induced RAW 264.7 macrophages and protects mice from lethal endotoxin shock. Food Chem Toxicol. 2013 Dec;62:847-55.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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