Hsp70-derived octapeptide

Hsp70-derived octapeptide

• CAS Number: 736171-62-3
• UNSPSC Description: Hsp70-derived octapeptide is a conserved octapeptide of the C-terminal end of Hsp70, which physically interacts with tetratricopeptide repeat (TPR) motifs[1][2].
• Target Antigen: HSP
• Type: Peptides
• Related Pathways: Cell Cycle/DNA Damage;Metabolic Enzyme/Protease
• Applications: COVID-19-immunoregulation
• Field of Research: Cancer; Neurological Disease; Infection
• Assay Protocol: https://www.medchemexpress.com/hsp70-derived-octapeptide.html
• Purity: 98.01
• Solubility: H2O : 1.82 mg/mL (ultrasonic;adjust pH to 1 with HCl)
• Smiles: O=C(O)C[C@@H](C(O)=O)NC([C@H](C(C)C)NC([C@H](CCC(O)=O)NC([C@H](CCC(O)=O)NC([C@H]([C@@H](C)CC)NC([C@H]([C@H](O)C)NC([C@H]1N(C(CN)=O)CCC1)=O)=O)=O)=O)=O)=O
• Molecular Weight: 858.89
• References & Citations: [1]Tutar Y, et al. Primate chaperones Hsc70 (constitutive) and Hsp70 (induced) differ functionally in supportinggrowth and prion propagation in Saccharomyces cerevisiae. Genetics. 2006 Feb;172(2):851-61.|[2]Kajander T, et al. Electrostatic interactions of Hsp-organizing protein tetratricopeptide domains with Hsp70 and Hsp90: computational analysis and protein engineering. J Biol Chem. 2009 Sep 11;284(37):25364-74.
• Shipping Conditions: Blue Ice
• Storage Conditions: -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
• Clinical Information: No Development Reported