HJC0350

• Description :

  HJC0350 is a potent and specific EPAC2 antagonist with an IC50 of 0.3 μM.

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H319, H332, H372, H400

• Target :

  Ras

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; MAPK/ERK Pathway

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/HJC0350.html

• Purity :

  98.11

• Solubility :

  DMSO : 33.33 mg/mL (ultrasonic)

• Smiles :

  O=S(N1C(C)=CC(C)=C1)(C2=C(C)C=C(C)C=C2C)=O

• Molecular Formula :

  C15H19NO2S

• Molecular Weight :

  277.38

• Precautions :

  H302, H319, H332, H372, H400

• References & Citations :

  [1]Chen H, et al. Identification and characterization of small molecules as potent and specific EPAC2 antagonists. J Med Chem. 2013 Feb 14;56 (3) :952-62.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [885434-70-8]