Roxatidine (Standard)

• Description:

  Roxatidine (Standard) is the analytical standard of Roxatidine. This product is intended for research and analytical applications. Roxatidine is an active metabolite of Roxatidine acetate hydrochloride, is a histamine H2-receptor antagonist. Roxatidine, an anti-ulcer agent, suppresses histamine release (thus inhibiting proton secretion) and inhibits the production of VEGF-1, an important marker of inflammation and angiogenesis. Anti-allergic inflammatory effect[1].

• UNSPSC:

  12352005

• Target:

  Histamine Receptor; Reference Standards

• Type:

  Reference Standards

• Related Pathways:

  GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling; Others

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/roxatidine-standard.html

• Smiles:

  O=C (NCCCOC1=CC=CC (CN2CCCCC2) =C1) CO

• Molecular Formula:

  C17H26N2O3

• Molecular Weight:

  306.40

• References & Citations:

  [1]Lee M, et al. Roxatidine attenuates mast cell-mediated allergic inflammation via inhibition of NF-κB and p38 MAPK activation. Sci Rep. 2017;7:41721. Published 2017 Jan 31.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference Standards

• CAS Number:

  78273-80-0