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Roxatidine (Standard)

CAT: 0804-HY-137941RSize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-137941RSize:1 Each
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Description
Roxatidine (Standard) is the analytical standard of Roxatidine. This product is intended for research and analytical applications. Roxatidine is an active metabolite of Roxatidine acetate hydrochloride, is a histamine H2-receptor antagonist. Roxatidine, an anti-ulcer agent, suppresses histamine release (thus inhibiting proton secretion) and inhibits the production of VEGF-1, an important marker of inflammation and angiogenesis. Anti-allergic inflammatory effect[1].
CAS Number
78273-80-0
UNSPSC
12352005
Target
Histamine Receptor; Reference Standards
Type
Reference Standards
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling; Others
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/roxatidine-standard.html
Smiles
O=C(NCCCOC1=CC=CC(CN2CCCCC2)=C1)CO
Molecular Formula
C17H26N2O3
Molecular Weight
306.40
References & Citations
[1]Lee M, et al. Roxatidine attenuates mast cell-mediated allergic inflammation via inhibition of NF-κB and p38 MAPK activation. Sci Rep. 2017;7:41721. Published 2017 Jan 31.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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