Deruxtecan analog 2

Deruxtecan analog 2

• CAS Number: 1599440-10-4
• UNSPSC Description: Deruxtecan analog 2 (example 9 P3) is a Deruxtecan (HY-13631E) analog. Deruxtecan analog 2 is a agent-linker conjugate composed of Camptothecin (HY-16560) and a linker. Camptothecin (CPT) is a Topo I inhibitor with antineoplastic activity against colorectal, breast, lung and ovarian cancers. Deruxtecan analog 2 can be used for the preparation anti-FGFR2 ADC[1].
• Target Antigen: Drug-Linker Conjugates for ADC
• Type: ADC Related
• Related Pathways: Antibody-drug Conjugate/ADC Related
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/deruxtecan-analog-2.html
• Purity: 99.56
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: O=C(N[C@H]1CCC2=C3C1=C(CN4C(C(COC([C@@]5(CC)O)=O)=C5C=C46)=O)C6=NC3=CC(F)=C2C)COCNC(CN)=O
• Molecular Weight: 579.58
• References & Citations: [1]Daly Christopher, et, al. Anti-FGFR2 antibodies and antibody-drug conjugates methods of use thereof. Patent WO2022087243.
• Shipping Conditions: Blue Ice
• Storage Conditions: -20°C (Powder, protect from light, stored under nitrogen)
• Clinical Information: No Development Reported