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Kresoxim-methyl

CAT: 0804-HY-125776-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-125776-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Kresoxim-methyl (BAS 490 F), a Strobilurin-based fungicide, inhibits the respiration at the complex III (cytochrome bc1 complex) . Kresoxim-methyl binds to complex III from yeast with an apparent Kd of 0.07 μM proving a high affinity for this enzyme[1][2].
CAS Number
143390-89-0
Product Name Alternative
BAS 490 F
UNSPSC
12352005
Hazard Statement
H351, H410
Target
Fungal; Mitochondrial Metabolism
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/kresoxim-methyl.html
Purity
99.83
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(OC)/C(C1=CC=CC=C1COC2=CC=CC=C2C)=N/OC
Molecular Formula
C18H19NO4
Molecular Weight
313.35
Precautions
H351, H410
References & Citations
[1]Roehl F. Binding of BAS 490 F to bc1-complex from yeast. Biochem Soc Trans. 1994;22 (1) :64S.|[2]Köhle H, et al. Biokinetic properties of BAS 490 F and some related compounds. Biochem Soc Trans. 1994;22 (1) :65S.|[3]Flampouri E, et al. Strobilurin fungicide kresoxim-methyl effects on a cancerous neural cell line: oxidant/antioxidant responses and in vitro migration. Toxicol Mech Methods. 2018;28 (9) :709-716.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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