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MUC5B Antibody

CAT: 0800-RQ6976Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ6976Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mucin 5B (MUC5B/Muc5b) is a protein that in humans is encoded by the MUC5B gene and by the Muc5b gene in mouse. This gene encodes a member of the mucin family of proteins, which are highly glycosylated macromolecular components of mucus secretions. This family member is the major gel-forming mucin in mucus. It is a major contributor to the lubricating and viscoelastic properties of whole saliva, normal lung mucus and cervical mucus. This gene has been found to be up-regulated in some human diseases, including sinus mucosa of chronic rhinosinusitis (CRS), CRS with nasal polyposis, chronic obstructive pulmonary disease (COPD) and H. pylori-associated gastric disease, and it may be involved in the pathogenesis of these diseases.
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 2-5 µg/mL, Direct ELISA: 0.1-0.5 µg/mL
UniProt
Q9HC84
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant human protein (amino acids A5688-V5762) was used as the immunogen for the MUC5B antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
IHC-P, Direct ELISA
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the MUC5B antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This MUC5B antibody is available for research use only.
Storage Conditions
After reconstitution, the MUC5B antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the MUC5B antibody should be determined by the researcher.
Image Legend
IHC staining of FFPE human rectal cancer tissue with MUC5B antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.

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