N-Acetylgalactosaminyltransferase 4
CAT:
804-HY-E70291-01
Size:
1 mg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
N-Acetylgalactosaminyltransferase 4
- UNSPSC Description: N-Acetylgalactosaminyltransferase 4 (GALNT4) is a glycosyltransferase capable of inhibiting the activation of ASK1. By directly binding to ASK1, N-Acetylgalactosaminyltransferase 4 suppresses its N-terminal dimerization and subsequent phosphorylation, leading to robust inactivation of downstream JNK/p38 and NF-κB signals, and thereby improving the prognosis of liver surgery[1].
- Target Antigen: Endogenous Metabolite; JNK; MAP3K; NF-κB; p38 MAPK
- Type: Enzyme
- Related Pathways: MAPK/ERK Pathway;Metabolic Enzyme/Protease;NF-κB
- Applications: Cancer-Kinase/protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/n-acetylgalactosaminyltransferase-4.html
- Solubility: 10 mM in DMSO
- Smiles: [N-Acetylgalactosaminyltransferase 4]
- References & Citations: [1]Zhou J, et al. N-acetylgalactosaminyltransferase-4 protects against hepatic ischemia/reperfusion injury by blocking apoptosis signal-regulating kinase 1 N-terminal dimerization. Hepatology. 2022;75(6):1446-1460.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported