Azure B (Standard)

Azure B (Standard)

• CAS Number: 531-55-5
• UNSPSC Description: Azure B (Standard) is the analytical standard of Azure B. This product is intended for research and analytical applications. Azure B is a cationic dye and the major metabolite of Methylene blue. Azure B is used in making Azure eosin stains for blood smear staining. Azure B is a high-potency, selective and reversible inhibitor of monoamine oxidases (MAO)-A, with IC50s of 11 and 968 nM for recombinant human MAO-A and MAO-B, respectively. Azure B possesses significant antidepressant-like effects[1][2].
• Target Antigen: Monoamine Oxidase
• Type: Reference Standards
• Related Pathways: Neuronal Signaling
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/azure-b-standard.html
• Smiles: CNC1=CC2=[S+]C3=C(C=CC(N(C)C)=C3)N=C2C=C1.[Cl-]
• Molecular Weight: 305.83
• References & Citations: [1]Löhr W,et al. The azure dyes: their purification and physicochemical properties. II. Purification of azure B. Stain Technol. 1975 May;50(3):149-56.|[2]Delport A, et al. Azure B and a synthetic structural analogue of methylene blue, ethylthioninium chloride, present with antidepressant-like properties. Life Sci. 2014 Nov 11;117(2):56-66.
• Shipping Conditions: Room temperature