Mouse Interleukin-11 Recombinant

CAT: 0421-90177-BSize: 10 µgDry Ice: NoHazardous: No
CAT#:0421-90177-BSize:10 µg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
IL-11 is secreted by bone marrow stromal cells (fibroblasts) and is produced also by a number of mesenchymal cells. The IL-11 receptor (alpha chain) utilizes gp130 as its signal transducer, which is also a component of other cytokine receptors. The alpha chain of the IL-11 receptor has been identified independently as Etl2. IL-11 promotes primary and secondary immune responsesin vitroandin vivoand modulates antigen-specific antibody reactions. IL-11 promotes the proliferation of IL-6 dependent plasmacytoma cell lines in the presence of neutralizing IL-6 antibodies. IL-11 also stimulates the T-cell dependent development of IgG-secreting B-cells in spleen cell cultures. IL-11 inhibits the differentiation of pre- adipocytes. It induces the synthesis of some acute phase proteins by hepatocytes.
Description
Recombinant IL-11 is a disulfide-linked monomer protein consisting of 179 amino acid residues, and migrates as an approximately 19 kDa protein under non-reducing conditions and reducing conditions in SDS-PAGE. Optimized DNA sequence encoding mouse Interleukin-11 mature chain was expressed inE. coli.
UniProt
P47873
Endotoxin
< 0.1 ng/µg (1 EU/µg), using the LAL gel clot method.
Purity
≥ 95% by SDS-PAGE and HPLC
Format
Lyophilized protein
Reconstitution
Reconstitute at 0.1-1.0 mg/ml in distilled water. This solution can then be diluted into other buffers. To maximize product collection from vial surface, vortex briefly and then spin down to recollect the liquid.
Shipping Conditions
Gel Packs or Dry Ice
Storage Conditions
The lyophilized protein is stable for at least 2 years from date of receipt when stored at -20°C. Upon reconstitution, store in working aliquots at +4°C for up to one month, or at -20°C for up to six months, in the presence of a carrier protein. Avoid repeated freeze/thaw cycles.
Calculated Molecular Weight
19 kDa
Formulation
Lyophilized from 0.2 µm filtered PBS, pH 7.

Related Products

CatalogName
90176-AHuman Interleukin-11 Recombinant
90176-BHuman Interleukin-11 Recombinant
90197-BMouse Interleukin-6 Recombinant
90194-BMouse Interleukin-4 Recombinant
90185-AMouse Interleukin-2 Recombinant
90189-AMouse Interleukin-3 Recombinant
90189-BMouse Interleukin-3 Recombinant
90174-AMouse Interleukin-10 Recombinant
90174-BMouse Interleukin-10 Recombinant
90192-BMouse Interleukin-33 Recombinant

Alternative Products

CatalogName
149702-01Il11, Recombinant, Mouse (Interleukin-11, IL-11, Interleukin 11)
7-00935Recombinant Mouse Interleukin-11
rAP-0629Interleukin-11 Mouse Recombinant
MBS553157-01Mouse Interleukin-11 Recombinant
PT_41238-01Interleukin-11 Mouse Recombinant (IL 11 Mouse)
360588-01Interleukin-11, Recombinant, Mouse (IL-11) discontinued
RPU53481-01Recombinant Mouse Interleukin 11 (IL11)
MBS957765-01Recombinant Mouse Interleukin-11 (Il11)
I8433-01GInterleukin 11, Recombinant, Mouse (IL-11, Interleukin-11, IL11) discontinued. See 149702
32-9082-500Recombinant Mouse Interleukin-11/IL-11 (N-His)

Popular Products