CARM1/HDAC2-IN-1
CAT:
804-HY-157388-05
Size:
10 mM / 1 mL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
CARM1/HDAC2-IN-1
- UNSPSC Description: CARM1/HDAC2-IN-1 (compound CH-1) is a dual inhibitor against CARM1 and HDAC2, with IC50 values of 3.71 nM and 4.07 nM, respectively. CARM1/HDAC2-IN-1 possesses antitumor activity[1].
- Target Antigen: HDAC; Histone Methyltransferase
- Type: Reference compound
- Related Pathways: Cell Cycle/DNA Damage;Epigenetics
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/carm1-hdac2-in-1.html
- Solubility: 10 mM in DMSO
- Smiles: CNCCNCC1=CC=CC(C2=NC(NC3=CC(OCCCCCCC(NO)=O)=CC=C3)=C(C(C4=C5C=CNC5=NC=C4)=N2)C)=C1
- Molecular Weight: 622.76
- References & Citations: [1]Liang S, et al. Discovery and biological evaluation of novel CARM1/HDAC2 dual-targeting inhibitors with anti-prostate cancer agents. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2241118.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported