Ganetespib (STA-9090)

CAT: 0421-27750-2Size: 10 mgDry Ice: NoHazardous: No
CAT#:0421-27750-2Size:10 mg
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Description
Ganetespib (also known as STA-9090) is a potent small-molecule inhibitor of heat shock protein 90 (IC50=4 nM) . It binds to the ATP pocket in the N-terminus of Hsp90, resulting in down-regulation of Hsp90 client protein levels. Being structurally unrelated to geldanamycin-derived Hsp90 inhibitors (17-AAG, 17-DMAG, and IPI-504), ganetespib has a unique triazolone-containing chemical structure and stands out other Hsp90 inhibitors in terms of potency, antitumor activity, and safety profile.
CAS Number
888216-25-9
Solubility
Soluble in DMSO
Molecular Formula
C20H20N4O3
Shipping Conditions
Room Temperature (continental US) or Gel Packs
Storage Conditions
Store at or below –20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day.
Calculated Molecular Weight
364.4 Da

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