OTX-015

• Background:

  Bromodomains have an important role in the targeting of chromatin-modifying enzymes to specific sites, including methyltransferases, HATs and transcription factors and regulate diverse biological processes from cell proliferation and differentiation to energy homeostasis and neurological processes.

• Description:

  OTX-015 is a potent new BRD-inhibitor with evident anti-proliferative activity in several cell lines representative of mature B-cell tumors.

• Purity:

  ≥ 98% by HPLC

• Solubility:

  Soluble in DMSO

• Molecular Formula:

  C25H22ClN5O2S

• Shipping Conditions:

  Room Temperature (continental US) or Gel Packs

• Storage Conditions:

  Store at or below –20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day.

• Calculated Molecular Weight:

  492 Da

• CAS Number:

  202590-98-5